Test-E 250 is a commonly referenced term for a black-market injectable anabolic-androgenic steroid (AAS) that contains testosterone enanthate at a concentration of 250 milligrams per milliliter (mg/ml). While testosterone enanthate is a legally prescribed medication for specific medical conditions, this particular product is sourced from illicit labs and is not intended for legal use.
Medical vs. black-market use
- Medical use: Under proper medical supervision, testosterone enanthate is approved to treat men with hypogonadism (abnormally low testosterone levels). It is administered via a professional and the dosage is carefully regulated.
- Black-market use: In the context of bodybuilding and performance enhancement, users self-administer Test-E 250 at dosages far higher than medically recommended. This misuse is illegal in many countries and poses serious health risks.
Significant health risks
Because Test-E 250 is manufactured by unregulated labs, its purity, sterility, and even the accuracy of its stated concentration are not guaranteed. Its use is associated with a wide range of severe and sometimes irreversible side effects.
Cardiovascular
- Increased risk of heart attack, stroke, and cardiovascular death.
- High blood pressure.
- Increased red blood cell count (polycythemia), which can lead to blood clots.
Hormonal
- Suppression of the body’s natural testosterone production, which can cause infertility and testicular shrinkage.
- Gynecomastia (male breast development).
- Significant hormonal imbalances.
Psychological
- Severe mood swings.
- Increased aggression (“roid rage”).
- Anxiety, paranoia, and depression.
Other physical effects
- Androgenic effects: Severe acne, oily skin, and accelerated male-pattern hair loss in those genetically predisposed.
- Liver and kidney damage: Long-term use can cause life-threatening problems, including liver tumors.
- Injection site issues: Pain, swelling, and potential infections from non-sterile injections.
- In women: Can cause irreversible masculinizing effects, such as a deepened voice and clitoral enlargement.





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