“Tren-A 100” refers to a black-market injectable anabolic-androgenic steroid (AAS) that contains 100 milligrams per milliliter (mg/ml) of trenbolone acetate. This product is unregulated, illegal for human use in many countries, and not approved by regulatory bodies like the U.S. Food and Drug Administration (FDA).
Active substance
- Trenbolone acetate: A fast-acting, synthetic derivative of the male hormone testosterone.
- Original use: The substance was originally developed for veterinary use, specifically to increase muscle growth and appetite in cattle.
Intended use by bodybuilders
Users illegally acquire Tren-A 100 for performance and physique enhancement, including:
- Rapid muscle gain: The steroid is known for its ability to produce significant and quick gains in lean muscle mass.
- Fat loss: It is often used during cutting cycles to help burn fat while preserving muscle.
- Increased strength: Users experience a marked increase in overall strength.
Severe health risks
Like other illicit steroids, Tren-A 100 poses significant health dangers due to its potent effects and unregulated production.
- Severe side effects: Users may experience a wide range of physical and psychological issues, including:
- Cardiovascular: Elevated blood pressure, high cholesterol, and potential damage to the heart and kidneys.
- Hormonal: Suppression of natural testosterone production, leading to infertility and testicular shrinkage in men.
- Psychological: Increased aggression (“roid rage”), paranoia, severe mood swings, and insomnia (“trensomnia”).
- Other physical effects: Severe acne, hair loss, and a distinctive, violent cough immediately after injection (“tren cough”).
- Irreversible virilization in women: Female users risk developing masculine characteristics such as a deepened voice and clitoral enlargement.
- Risk of contamination: As a black-market product, Tren-A 100 may be contaminated or incorrectly dosed, further increasing health risks.





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