Test-E 400 is a black-market injectable anabolic-androgenic steroid (AAS) that contains 400 milligrams per milliliter (mg/ml) of testosterone enanthate. It is manufactured by illicit drug labs for the purpose of performance and physique enhancement, and its use is illegal without a prescription in many countries.
Active substance
- Testosterone enanthate: This is a long-acting ester of the male hormone testosterone. The “E” stands for “enanthate,” and the “400” refers to the high concentration of the active steroid compound.
- Medical use: Medically, a much lower dose of testosterone enanthate is FDA-approved to treat men with hypogonadism (low testosterone), delayed puberty in boys, and some forms of breast cancer in women. In these cases, it is administered by a healthcare professional.
Illegal use in bodybuilding
Bodybuilders and athletes illegally obtain Test-E 400 from the black market for performance enhancement. The high concentration is sought to achieve rapid gains in muscle mass and strength. Typical bodybuilding dosages are far higher than those prescribed for medical use.
Significant health risks
As an unregulated, black-market product, Test-E 400 carries significant health risks. It is not subject to quality controls, meaning its true strength, purity, and sterility cannot be guaranteed. The use of such a high-dose steroid is associated with a wide range of severe side effects:
- Cardiovascular: Elevated blood pressure, high cholesterol, and increased risk of heart attack and stroke.
- Hormonal: Suppression of natural testosterone production, which can lead to infertility, testicular shrinkage, and gynecomastia (male breast development).
- Psychological: Severe mood swings, aggression (“roid rage”), depression, anxiety, and paranoia.
- Androgenic: Severe acne, oily skin, and accelerated male-pattern hair loss in genetically predisposed individuals.
- Liver: The potential for altered liver function.
- Other: Women using the steroid risk developing irreversible masculine features, such as a deepened voice and clitoral enlargement.
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